Despite Genetic Iron Overload, Hfe‐Hemochromatosis Mice Do Not Show Bone Loss

Despite Genetic Iron Overload, Hfe‐Hemochromatosis Mice Do Not Show Bone Loss

ABSTRACT One of the most prevalent genetic iron overload disorders in Caucasians is caused by mutations in the HFE gene. Both HFE patients and Hfe‐mouse models develop a progressive accumulation of iron in the parenchymal cells of various tissues, eventually resulting in liver cirrhosis, hepatocellu...

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Bibliographic Details
Main Authors: Alessa Wagner, Betül Alan, Dilay Yilmaz, Mubashir Ahmad, Peng Liu, Naveen Kumar Tangudu, Jan P Tuckermann, Maja Vujic Spasic
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:JBMR Plus
Subjects:
HFE‐HEMOCHROMATOSIS
IRON
BONE
OSTEOPOROSIS
OSTEOBLAST/OSTEOCLASTS
Online Access:https://doi.org/10.1002/jbm4.10206

Internet

https://doi.org/10.1002/jbm4.10206

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