Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activation.

Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activation.

Many studies have shown that microglia in the activated state may be neurotoxic. It has been proven that uncontrolled or over-activated microglia play an important role in many neurodegenerative disorders. Bone marrow-derived mesenchymal stem cells (BMSCs) have been shown in many animal models to ha...

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Bibliographic Details
Main Authors: Ke Yan, Run Zhang, Chengmei Sun, Lei Chen, Peng Li, Yi Liu, Lingmei Peng, Haitao Sun, Kun Qin, Fanfan Chen, Weiyi Huang, Yuxin Chen, Bingke Lv, Mouxuan Du, Yuxi Zou, Yingqian Cai, Lingsha Qin, Yanping Tang, Xiaodan Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877190?pdf=render

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http://europepmc.org/articles/PMC3877190?pdf=render

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