Pseudomonas aeruginosa Pore-Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis

Pseudomonas aeruginosa Pore-Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis

Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, ExlB, showing that ExlA and ExlB define a new active two-part...

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Bibliographic Details
Main Authors: Pauline Basso, Michel Ragno, Sylvie Elsen, Emeline Reboud, Guillaume Golovkine, Stephanie Bouillot, Philippe Huber, Stephen Lory, Eric Faudry, Ina Attrée, Samuel I. Miller
Format: Article
Language:English
Published: American Society for Microbiology 2017-01-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e02250-16

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http://mbio.asm.org/cgi/content/full/8/1/e02250-16

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