GLT1 overexpression in SOD1G93A mouse cervical spinal cord does not preserve diaphragm function or extend disease

GLT1 overexpression in SOD1G93A mouse cervical spinal cord does not preserve diaphragm function or extend disease

Amyotrophic lateral sclerosis (ALS) is characterized by relatively rapid degeneration of both upper and lower motor neurons, with death normally occurring 2–5 years following diagnosis primarily due to respiratory paralysis resulting from phrenic motor neuron (PhMN) loss and consequent diaphragm den...

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Bibliographic Details
Main Authors: Ke Li, Tamara J. Hala, Suneil Seetharam, David J. Poulsen, Megan C. Wright, Angelo C. Lepore
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Neurobiology of Disease
Subjects:
ALS
Amyotrophic laterals sclerosis
Cervical spinal cord
Phrenic motor neuron
Diaphragm
GLT1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115000820

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http://www.sciencedirect.com/science/article/pii/S0969996115000820

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