Regulatory T cells in γ irradiation-induced immune suppression.

Sublethal total body γ irradiation (TBI) of mammals causes generalized immunosuppression, in part by induction of lymphocyte apoptosis. Here, we provide evidence that a part of this immune suppression may be attributable to dysfunction of immune regulation. We investigated the effects of sublethal T...

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Bibliographic Details
Main Authors: Hugh I McFarland, Montserrat Puig, Lucja T Grajkowska, Kazuhide Tsuji, Jay P Lee, Karen P Mason, Daniela Verthelyi, Amy S Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378522?pdf=render