Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a]

Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a]

The cellular and molecular mechanisms responsible for lipoprotein [a] (Lp[a]) catabolism are unknown. We examined the plasma clearance of Lp[a] and LDL in mice using lipoproteins isolated from human plasma coupled to radiolabeled tyramine cellobiose. Lipoproteins were injected into wild-type, LDL re...

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Bibliographic Details
Main Authors: William J. Cain, John S. Millar, Adam S. Himebauch, Uwe J.F. Tietge, Cyrille Maugeais, David Usher, Daniel J. Rader
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Journal of Lipid Research
Subjects:
kidney
tissue distribution
kinetics
LDL receptor
apolipoprotein E
asialoglycoprotein receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032856X

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http://www.sciencedirect.com/science/article/pii/S002222752032856X

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