Nafamostat Mesilate Is an Extremely Potent Inhibitor of Human Tryptase
Previously, nafamostat mesilate was found to be a potent inhibitor of human tryptase. In present study, we performed a kinetic study to determine its Ki value for tryptase and compared it with that of gabexate mesilate. Nafamostat mesilate inhibited human tryptase in a competitive manner. The appare...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319326416 |