De Novo Sequencing of Top-Down Tandem Mass Spectra: A Next Step towards Retrieving a Complete Protein Sequence
De novo sequencing of tandem (MS/MS) mass spectra represents the only way to determine the sequence of proteins from organisms with unknown genomes, or the ones not directly inscribed in a genome—such as antibodies, or novel splice variants. Top-down mass spectrometry provides new opportunities for...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-02-01
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| Series: | Proteomes |
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| Online Access: | http://www.mdpi.com/2227-7382/5/1/6 |