The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily...

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Bibliographic Details
Main Authors: Jonathan G Van Vranken, Mi-Young Jeong, Peng Wei, Yu-Chan Chen, Steven P Gygi, Dennis R Winge, Jared Rutter
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/17828