CDK Phosphorylation of Translation Initiation Factors Couples Protein Translation with Cell-Cycle Transition

Summary: Protein translation in eukaryotes is cell-cycle dependent, with translation rates more robust in G1 phase of the cell cycle than in mitosis. However, whether the fundamental cell-cycle control machinery directly activates protein translation during the G1/S cell-cycle transition remains unk...

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Bibliographic Details
Main Authors: Tai An, Yi Liu, Stéphane Gourguechon, Ching C. Wang, Ziyin Li
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718318394