RNAi targeting of West Nile virus in mosquito midguts promotes virus diversification.

West Nile virus (WNV) exists in nature as a genetically diverse population of competing genomes. This high genetic diversity and concomitant adaptive plasticity has facilitated the rapid adaptation of WNV to North American transmission cycles and contributed to its explosive spread throughout the Ne...

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Bibliographic Details
Main Authors: Doug E Brackney, Jennifer E Beane, Gregory D Ebel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2698148?pdf=render