Enhanced anxiety observed in cocaine withdrawn rats is associated with altered reactivity of the dorsomedial prefrontal cortex.

Discontinuation of drug intake in cocaine abusers commonly produces a variety of adverse withdrawal symptoms among which anxiety and depression-related behavior are prevailing during the initial period of abstinence. The aim of this study was to provide further insight into the neurobiological dysre...

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Bibliographic Details
Main Authors: Cynthia El Hage, Virginie Rappeneau, Adeline Etievant, Anne-Laure Morel, Hélène Scarna, Luc Zimmer, Anne Bérod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3420872?pdf=render