Stat2-Drp1 mediated mitochondrial mass increase is necessary for pro-inflammatory differentiation of macrophages

Macrophage recruitment and pro-inflammatory differentiation are hallmarks of various diseases, including infection and sepsis. Although studies suggest that mitochondria may regulate macrophage immune responses, it remains unclear whether mitochondrial mass affects macrophage pro-inflammatory differ...

Full description

Bibliographic Details
Main Authors: Weihua Yu, Xin Wang, Jiuzhou Zhao, Rui Liu, Jiangzheng Liu, Zhao Wang, Jie Peng, Hao Wu, Xiaodi Zhang, Zi Long, Deqin Kong, Wenli Li, Chunxu Hai
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309666