Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups

Background Drug therapy yields different results depending on its recipient population. Cisplatin, a commonly used chemotherapeutic agent, causes different levels of resistance and side effects for different patients, but the mechanism(s) are presently unknown. It has been assumed that this variatio...

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Bibliographic Details
Main Authors: Sina Abedi, Gregory Yung, Shari R. Atilano, Kunal Thaker, Steven Chang, Marilyn Chwa, Kevin Schneider, Nitin Udar, Daniela Bota, M. Cristina Kenney
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/9908.pdf