Pre-Treatment Neutrophil Count as a Predictor of Antituberculosis Therapy Outcomes: A Multicenter Prospective Cohort Study

BackgroundNeutrophils have been associated with lung tissue damage in many diseases, including tuberculosis (TB). Whether neutrophil count can serve as a predictor of adverse treatment outcomes is unknown.MethodsWe prospectively assessed 936 patients (172 HIV-seropositive) with culture-confirmed pul...

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Main Authors: Anna Cristina C. Carvalho, Gustavo Amorim, Mayla G. M. Melo, Ana Karla A. Silveira, Pedro H. L. Vargas, Adriana S. R. Moreira, Michael S. Rocha, Alexandra B. Souza, María B. Arriaga, Mariana Araújo-Pereira, Marina C. Figueiredo, Betina Durovni, José R. Lapa-e-Silva, Solange Cavalcante, Valeria C. Rolla, Timothy R. Sterling, Marcelo Cordeiro-Santos, Bruno B. Andrade, Elisangela C. Silva, Afrânio L. Kritski, the RePORT Brazil consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661934/full