Clinical Validation of Automatable Gaussian Normalized CBV in Brain Tumor Analysis: Superior Reproducibility and Slightly Better Association with Survival than Current Standard Manual Normal Appearing White Matter Normalization

PURPOSE: To validate Gaussian normalized cerebral blood volume (GN-nCBV) by association with overall survival (OS) in newly diagnosed glioblastoma patients and compare this association with current standard white matter normalized cerebral blood volume (WN-nCBV). METHODS: We retrieved spin-echo echo...

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Bibliographic Details
Main Authors: Lei Qin, Xiang Li, Angie Li, Suchun Cheng, Jinrong Qu, Katherine Reinshagen, Jiani Hu, Nathan Himes, Gao Lu, Xiaoyin Xu, Geoffrey S. Young
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318302870