Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection

Escherichia coli Nissle 1917 Enhances Innate and Adaptive Immune Responses in a Ciprofloxacin-Treated Defined-Microbiota Piglet Model of Human Rotavirus Infection

Rotavirus (RV) is a primary cause of malabsorptive diarrhea in children and is associated with significant morbidity and mortality, especially in developing countries. The use of antibiotics exacerbates intestinal microbial imbalance and results in the persistence of RV-induced diarrhea.

Bibliographic Details
Main Authors: Husheem Michael, Francine C. Paim, Stephanie N. Langel, Ayako Miyazaki, David D. Fischer, Juliet Chepngeno, Joshua Amimo, Loic Deblais, Gireesh Rajashekara, Linda J. Saif, Anastasia N. Vlasova
Format: Article
Language:English
Published: American Society for Microbiology 2021-04-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00074-21

Internet

https://journals.asm.org/doi/10.1128/mSphere.00074-21

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