Functional and structural neural network characterization of serotonin transporter knockout rats.

Brain serotonin homeostasis is crucially maintained by the serotonin transporter (5-HTT), and its down-regulation has been linked to increased vulnerability for anxiety- and depression-related behavior. Studies in 5-HTT knockout (5-HTT(-/-)) rodents have associated inherited reduced functional expre...

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Bibliographic Details
Main Authors: Kajo van der Marel, Judith R Homberg, Willem M Otte, Rick M Dijkhuizen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3581479?pdf=render