High Antibodies to VAR2CSA in Response to Malaria Infection Are Associated With Improved Birthweight in a Longitudinal Study of Pregnant Women

High Antibodies to VAR2CSA in Response to Malaria Infection Are Associated With Improved Birthweight in a Longitudinal Study of Pregnant Women

IntroductionPregnant women have an increased risk of P. falciparum infection, which is associated with low birth weight and preterm delivery. VAR2CSA, a variant surface antigen expressed on the parasitized erythrocyte surface, enables sequestration in the placenta. Few studies have prospectively exa...

Full description

Bibliographic Details
Main Authors: Alistair R. D. McLean, D. Herbert Opi, Danielle I. Stanisic, Julia C. Cutts, Gaoqian Feng, Alice Ura, Ivo Mueller, Stephen J. Rogerson, James G. Beeson, Freya J. I. Fowkes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
VAR2CSA antibodies
birthweight
placental infection
Papua New Guinea
malaria in pregnancy (MiP)
Plasmodium falciparum
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.644563/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.644563/full

Similar Items