Liquid-liquid extraction pretreatment samples method used for pharmacokinetic study of rhubarb in rats after oral administrated

Objective: Pretreatment of biological samples is the most critical step in pharmacokinetic studies, especially pre-treatment of plasma samples. The pretreatment of biological samples in pharmacokinetic study of Traditional Chinese Medicines (TCM) is difficult due to the complexity of the ingredients...

Full description

Bibliographic Details
Main Authors: Hongmei Lin, Longfei Lin, Lingyan Xu, Yuanping Xie, Zhenzhen Xia, Qing Wu
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Journal of Traditional Chinese Medical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754817301242