VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy

VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy

Abstract VISTA (V-domain immunoglobulin suppressor of T cell activation) is a well-established immune regulatory receptor. However, pre-clinical investigations indicated more complicated influences of VISTA on cancer immunity than previously recognized. Here, we review the current knowledge on the t...

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Bibliographic Details
Main Authors: Xing Huang, Xiaozhen Zhang, Enliang Li, Gang Zhang, Xun Wang, Tianyu Tang, Xueli Bai, Tingbo Liang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Hematology & Oncology
Subjects:
Cancer immunotherapy
Co-inhibition
Co-stimulation
Immune checkpoint
VISTA
Online Access:http://link.springer.com/article/10.1186/s13045-020-00917-y

Internet

http://link.springer.com/article/10.1186/s13045-020-00917-y

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