The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis. In modular PKSs, the polyketide chain is assembled by the successive condensation of activated carboxylic...

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Bibliographic Details
Main Authors: David H. Kwan, Frank Schulz
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Molecules
Subjects:
polyketides
polyketide synthase
stereochemistry
ketosynthase
acyltransferase
ketoreductase
dehydratase
enoylreductase
Online Access:http://www.mdpi.com/1420-3049/16/7/6092/

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http://www.mdpi.com/1420-3049/16/7/6092/

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