Potential interaction between lysophosphatidic acid and tumor-associated macrophages in ovarian carcinoma

Potential interaction between lysophosphatidic acid and tumor-associated macrophages in ovarian carcinoma

Abstract Ovarian carcinoma is the deadliest type of gynecological cancer. The unique tumor microenvironment enables specific and efficient metastasis, weakens immunological monitoring, and mediates drug resistance. Tumor associated macrophages (TAMs) are a crucial part of the TME and are involved in...

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Bibliographic Details
Main Authors: Ying Feng, Meizhu Xiao, Zihan Zhang, Ran Cui, Xuan Jiang, Shuzhen Wang, Huimin Bai, Chongdong Liu, Zhenyu Zhang
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Inflammation
Subjects:
Ovarian carcinoma
Tumor microenvironment
Tumor associated macrophage
LPA
LPAR
PI3K/AKT/mTOR
Online Access:http://link.springer.com/article/10.1186/s12950-020-00254-4

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http://link.springer.com/article/10.1186/s12950-020-00254-4

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