Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.

Tether proteins attach the endoplasmic reticulum (ER) to other cellular membranes, thereby creating contact sites that are proposed to form platforms for regulating lipid homeostasis and facilitating non-vesicular lipid exchange. Sterols are synthesized in the ER and transported by non-vesicular mec...

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Bibliographic Details
Main Authors: Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Jeremy S Dittman, William J Rice, Robin B Chan, Gilbert Di Paolo, Christopher T Beh, Anant K Menon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2003864

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https://doi.org/10.1371/journal.pbio.2003864

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