Uric acid induced inflammatory responses in endothelial cells via up-regulating(pro)renin receptor

Uric acid induced inflammatory responses in endothelial cells via up-regulating(pro)renin receptor

Hyperuricemia is an important risk factor for vascular inflammation, yet the potential mechanisms of uric acid (UA) in endothelial cells are not well understood. UA has been found to stimulate renin-angiotensin system (RAS) activation in human umbilical vein endothelial cells (HUVECs). (Pro)renin re...

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Bibliographic Details
Main Authors: Xiaolei Yang, Jie Gu, Haichen Lv, Huihua Li, Yunpeng Cheng, Yang Liu, Yinong Jiang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Uric acid
Hyperuricemia
Atherosclerosis
Intercellular adhesion molecule-1 (ICAM-1)
Microfluidic chip
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218334541

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http://www.sciencedirect.com/science/article/pii/S0753332218334541

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