Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection.

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), infects one third of the world's population. Among these infections, clinical isolates belonging to the W-Beijing appear to be emerging, representing about 50% of Mtb isolates in East Asia, and about 13% of all Mtb isol...

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Main Authors: Radha Gopal, Leticia Monin, Samantha Slight, Uzodinma Uche, Emmeline Blanchard, Beth A Fallert Junecko, Rosalio Ramos-Payan, Christina L Stallings, Todd A Reinhart, Jay K Kolls, Deepak Kaushal, Uma Nagarajan, Javier Rangel-Moreno, Shabaana A Khader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4022785?pdf=render