Prevalence and effect of pre-treatment drug resistance on the virological response to antiretroviral treatment initiated in HIV-infected children – a EuroCoord-CHAIN-EPPICC joint project

Prevalence and effect of pre-treatment drug resistance on the virological response to antiretroviral treatment initiated in HIV-infected children – a EuroCoord-CHAIN-EPPICC joint project

Abstract Background Few studies have evaluated the impact of pre-treatment drug resistance (PDR) on response to combination antiretroviral treatment (cART) in children. The objective of this joint EuroCoord-CHAIN-EPPICC/PENTA project was to assess the prevalence of PDR mutations and their associatio...

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Bibliographic Details
Main Authors: Nicole Ngo-Giang-Huong, Linda Wittkop, Ali Judd, Peter Reiss, Tessa Goetghebuer, Dan Duiculescu, Antoni Noguera-Julian, Magdalena Marczynska, Carlo Giacquinto, Luminita Ene, Jose T. Ramos, Cristina Cellerai, Thomas Klimkait, Benedicte Brichard, Niels Valerius, Caroline Sabin, Ramon Teira, Niels Obel, Christoph Stephan, Stéphane de Wit, Claire Thorne, Diana Gibb, Christine Schwimmer, Maria Athena Campbell, Deenan Pillay, Marc Lallemant, The EuroCoord-CHAIN-EPPICC joint project study group
Format: Article
Language:English
Published: BMC 2016-11-01
Series:BMC Infectious Diseases
Subjects:
HIV
Children
Pre-treatment drug resistance mutations
Virological failure
First-line combination antiretroviral therapy
Online Access:http://link.springer.com/article/10.1186/s12879-016-1968-2

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http://link.springer.com/article/10.1186/s12879-016-1968-2

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