Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection.

Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection.

Clostridium difficile is a Gram-positive, spore-forming anaerobic bacterium that infects the colon, causing symptoms ranging from infectious diarrhea to fulminant colitis. In the last decade, the number of C. difficile infections has dramatically risen, making it the leading cause of reported hospit...

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Bibliographic Details
Main Authors: Reece J Knippel, Joseph P Zackular, Jessica L Moore, Arianna I Celis, Andy Weiss, M Kay Washington, Jennifer L DuBois, Richard M Caprioli, Eric P Skaar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007486

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https://doi.org/10.1371/journal.ppat.1007486

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