Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes

Hydrogen/Deuterium eXchange Mass Spectrometry (HDX-MS) is a rapidly evolving technique for analyzing structural features and dynamic properties of proteins. It may stand alone or serve as a complementary method to cryo-electron-microscopy (EM) or other structural biology approaches. HDX-MS is capabl...

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Bibliographic Details
Main Authors: Oliver Ozohanics, Attila Ambrus
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/10/11/286