Pathogen Evasion of Chemokine Response Through Suppression of CXCL10

Pathogen Evasion of Chemokine Response Through Suppression of CXCL10

Clearance of intracellular pathogens, such as Leishmania (L.) major, depends on an immune response with well-regulated cytokine signaling. Here we describe a pathogen-mediated mechanism of evading CXCL10, a chemokine with diverse antimicrobial functions, including T cell recruitment. Infection with...

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Bibliographic Details
Main Authors: Alejandro L. Antonia, Kyle D. Gibbs, Esme D. Trahair, Kelly J. Pittman, Amelia T. Martin, Benjamin H. Schott, Jeffrey S. Smith, Sudarshan Rajagopal, J. Will Thompson, Richard Lee Reinhardt, Dennis C. Ko
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
CXCL10
CXCR3
Leishmania
gp63
leishmanolysin
Chlamydia
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00280/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00280/full

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