Analysis of the mitochondrial 4977 bp deletion in patients with hepatocellular carcinoma

Mutations in the mitochondrial (mt) genome that result in mt dysfunction, have long been proposed to play important roles in the pathogenesis of hepatocellular carcinoma (HCC). Among these, the common mtDNA 4977 bp deletion is one of the most frequent mutations observed in various cancers. To unders...

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Bibliographic Details
Main Authors: Guo ZS, Jin CL, Yao ZJ, Wang YM, Xu BT
Format: Article
Language:English
Published: Sciendo 2017-06-01
Series:Balkan Journal of Medical Genetics
Subjects:
Online Access:https://doi.org/10.1515/bjmg-2017-0006