Adaptive copy number evolution in malaria parasites.

Adaptive copy number evolution in malaria parasites.

Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive selection is poorly understood. The first gene in the Plasmodium folate biosynthesis pathway, GTP-cyclohydrolase I (gch1), shows extensive CNP. We provide compelling evide...

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Bibliographic Details
Main Authors: Shalini Nair, Becky Miller, Marion Barends, Anchalee Jaidee, Jigar Patel, Mayfong Mayxay, Paul Newton, François Nosten, Michael T Ferdig, Tim J C Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2570623?pdf=render

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http://europepmc.org/articles/PMC2570623?pdf=render

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