Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis
Abstract Extracellular matrix glycoprotein Reelin is associated with tumor metastasis and prognosis in various malignancies. However, its effects on multiple myeloma (MM) are not fully understood. Here, we investigated the regulatory effects of Reelin on MM and its underlying pathogenic mechanisms....
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00608-8 |