Exploring the Scope of Tandem Palladium and Isothiourea Relay Catalysis for the Synthesis of α-Amino Acid Derivatives

Exploring the Scope of Tandem Palladium and Isothiourea Relay Catalysis for the Synthesis of α-Amino Acid Derivatives

The scope and limitations of a tandem N-allylation/[2,3]-rearrangement protocol are investigated through the incorporation of a variety of functional groups within an allylic phosphate precursor. This method uses readily accessible N,N-dimethylglycine aryl esters and functionalized allylic phosphate...

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Bibliographic Details
Main Authors: Jacqueline Bitai, Alexandra M. Z. Slawin, David B. Cordes, Andrew D. Smith
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
isothiourea
palladium
enantioselective catalysis
amino acids
[2,3]-rearrangement
<i>N</i>-allylation
Online Access:https://www.mdpi.com/1420-3049/25/10/2463

Internet

https://www.mdpi.com/1420-3049/25/10/2463

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