Insulin promotes amyloid precursor protein metabolism in an Alzheimer's disease cell model

Objective To investigate how insulin affects the metabolism of amyloid precursor protein (APP) in a cell model of Alzheimer's disease (AD). Methods Human neuroblastoma SH-SY5Y cells and the nonneural cell lines HEK293 and 2EB2 were treated with different concentrations of insulin for 48 h, and...

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Bibliographic Details
Main Authors: HU Rong, WANG Dan, LOU Dandan, LI Tingyu, ZHOU Weihui, SONG Weihong
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-06-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202001195.htm