Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats

Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats

Alcoholism is a chronically relapsing disorder characterized by high alcohol intake and a negative emotional state during abstinence, which contributes to excessive drinking and susceptibility to relapse. Stress, dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and alterations in gluco...

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Bibliographic Details
Main Authors: Federica Benvenuti, Nazzareno Cannella, Serena Stopponi, Laura Soverchia, Massimo Ubaldi, Veronica Lunerti, Valentina Vozella, Bryan Cruz, Marisa Roberto, Roberto Ciccocioppo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
alcohol use disorder
stress
alcohol preferring rats
glucocorticoids
mifepristone
alcohol self-administration
Online Access:https://www.mdpi.com/1422-0067/22/8/4184

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https://www.mdpi.com/1422-0067/22/8/4184

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