Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase

Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase

The human enzyme D-3-phosphoglycerate dehydrogenase (hPHGDH) catalyzes the reversible dehydrogenation of 3-phosphoglycerate (3PG) into 3-phosphohydroxypyruvate (PHP) using the NAD<sup>+</sup>/NADH redox cofactor, the first step in the phosphorylated pathway producing L-serine. We focused...

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Bibliographic Details
Main Authors: Giulia Murtas, Giorgia Letizia Marcone, Alessio Peracchi, Erika Zangelmi, Loredano Pollegioni
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
L-serine
D-serine
NAD
biochemical properties
metabolism
NMDA receptor
Online Access:https://www.mdpi.com/1422-0067/22/8/4231

Internet

https://www.mdpi.com/1422-0067/22/8/4231

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