Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice.

A hallmark of aging-related organ deterioration is a dysregulated immune response characterized by pathologic leukocyte infiltration of affected tissues. Mechanisms and genes involved are as yet unknown. To identify genes associated with aging-related renal infiltration, we analyzed kidneys from age...

Full description

Bibliographic Details
Main Authors: Yuan Huang, Christina R Caputo, Gerda A Noordmans, Saleh Yazdani, Luiz Henrique Monteiro, Jaap van den Born, Harry van Goor, Peter Heeringa, Ron Korstanje, Jan-Luuk Hillebrands
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956762?pdf=render