Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway

Apigenin inhibits fibroblast proliferation and reduces epidural fibrosis by regulating Wnt3a/β-catenin signaling pathway

Abstract Background Failed back surgery syndrome (FBSS) is a common complication after the laminectomy. Epidural fibrosis is the major cause of lower back pain and other complications. Numerous studies have shown that apigenin (API) could treat various fibrotic diseases by regulating various signali...

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Bibliographic Details
Main Authors: Rui Jiao, Hui Chen, Qi Wan, Xiaobo Zhang, Jihang Dai, Xiaolei Li, Lianqi Yan, Yu Sun
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Apigenin
Epidural fibrosis
Wnt3a
Fibroblast proliferation
Online Access:http://link.springer.com/article/10.1186/s13018-019-1305-8

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http://link.springer.com/article/10.1186/s13018-019-1305-8

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