Characterisation of bladder sensory neurons in the context of myelination, receptors for pain modulators, and acute responses to bladder inflammation

Bladder sensation is mediated by lumbosacral dorsal root ganglion neurons and is essential for normal voiding and nociception. Numerous electrophysiological, structural and molecular changes occur in these neurons following inflammation. Defining which neurons undergo these changes is critical for u...

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Bibliographic Details
Main Authors: Shelley L Forrest, Peregrine B Osborne, Janet R Keast
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00206/full