ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease
HDL-like particles in human cerebrospinal fluid (CSF) promote the efflux of cholesterol from astrocytes toward the neurons that rely on this supply for their functions. We evaluated whether cell cholesterol efflux capacity of CSF (CSF-CEC) is impaired in Alzheimer's disease (AD) by analyzing AD...
Main Authors: | Cinzia Marchi, Maria Pia Adorni, Paolo Caffarra, Nicoletta Ronda, Marco Spallazzi, Federica Barocco, Daniela Galimberti, Franco Bernini, Francesca Zimetti |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-08-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520322392 |
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