Fluorescence lifetime imaging unravels C. trachomatis metabolism and its crosstalk with the host cell.

Chlamydia trachomatis is an obligate intracellular bacterium that alternates between two metabolically different developmental forms. We performed fluorescence lifetime imaging (FLIM) of the metabolic coenzymes, reduced nicotinamide adenine dinucleotides [NAD(P)H], by two-photon microscopy for separ...

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Bibliographic Details
Main Authors: Márta Szaszák, Philipp Steven, Kensuke Shima, Regina Orzekowsky-Schröder, Gereon Hüttmann, Inke R König, Werner Solbach, Jan Rupp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3136453?pdf=render