Selection for robustness in mutagenized RNA viruses.
Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC1892351?pdf=render |