Hypoxia induced changes in miRNAs and their target mRNAs in extracellular vesicles of esophageal squamous cancer cells

Background Extracellular vesicles (EVs) are endogenous membrane vesicles with a diameter of 30–200 nm. It has been reported that hypoxic cancer cells can release numerous EVs to mediate multiple regional and systemic effects in the tumor microenvironment. Methods In this study, we used ultracentrifu...

Full description

Bibliographic Details
Main Authors: Fangyu Chen, Li Chu, Jie Li, Yu Shi, Bing Xu, Junjie Gu, Xijuan Yao, Meng Tian, Xi Yang, Xinchen Sun
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.13295