Discovering RNA-Protein Interactome by Using Chemical Context Profiling of the RNA-Protein Interface

RNA-protein (RNP) interactions generally are required for RNA function. At least 5% of human genes code for RNA-binding proteins. Whereas many approaches can identify the RNA partners for a specific protein, finding the protein partners for a specific RNA is difficult. We present a machine-learning...

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Bibliographic Details
Main Authors: Marc Parisien, Xiaoyun Wang, George Perdrizet, II, Corissa Lamphear, Carol A. Fierke, Ketan C. Maheshwari, Michael J. Wilde, Tobin R. Sosnick, Tao Pan
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001770