Chiral twisting in a bacterial cytoskeletal polymer affects filament size and orientation

The actin homolog MreB directs cell-wall insertion and maintains cell shape in many rod-shaped bacteria. Here, Shi et al. perform molecular dynamics simulations for MreB to extract mechanical parameters for inputs into a coarse-grained biophysical polymer model that predicts MreB filament properties...

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Bibliographic Details
Main Authors: Handuo Shi, David A. Quint, Gregory M. Grason, Ajay Gopinathan, Kerwyn Casey Huang
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14752-9