Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity.

OBJECTIVE: Familial longevity is marked by enhanced peripheral but not hepatic insulin sensitivity. The liver has a critical role in the pathogenesis of hepatic insulin resistance. Therefore we hypothesized that the extent of liver steatosis would be similar between offspring of long-lived siblings...

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Bibliographic Details
Main Authors: Michiel Sala, Lucia J M Kroft, Boudewijn Röell, Jeroen van der Grond, P Eline Slagboom, Simon P Mooijaart, Albert de Roos, Diana van Heemst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3954617?pdf=render