The importance of MHC class II in allogeneic bone marrow transplantation and chimerism-based solid organ tolerance in a rat model.

The importance of MHC class II in allogeneic bone marrow transplantation and chimerism-based solid organ tolerance in a rat model.

Mixed hematopoietic chimerism enables donor-specific tolerance for solid organ grafts. This study evaluated the influence of different serological major histocompatibility complex disparities on chimerism development, graft-versus-host disease incidence and subsequently on solid organ tolerance in a...

Full description

Bibliographic Details
Main Authors: Kai Timrott, Oliver Beetz, Felix Oldhafer, Jürgen Klempnauer, Florian W R Vondran, Mark D Jäger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233497

Internet

https://doi.org/10.1371/journal.pone.0233497

Similar Items