Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment

Phosphoinositide 3-kinases (PI3Ks) are a diverse family of enzymes which regulate various critical biological processes, such as cell proliferation and survival. Class (I) PI3Ks (PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ) mediate the phosphorylation of the inositol ring at position D3 leading to the generation...

Full description

Bibliographic Details
Main Authors: David Gyori, Tamara Chessa, Phillip T. Hawkins, Len R. Stephens
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/3/24