Posttransplant Lymphoproliferative Disease after Lung Transplantation
Posttransplant lymphoproliferative disease (PTLD) after lung transplantation occurs due to immunosuppressant therapy which limits antiviral host immunity and permits Epstein-Barr viral (EBV) replication and transformation of B cells. Mechanistically, EBV survives due to latency, escape from cytotoxi...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1155/2013/430209 |